Coronary Disease Comes Slowly To The Basis of Blood Pressure

The People who , the Patients with a  clogged and hardened arteries who already have increase their blood pressure under control may be  benefit from an inductive  additional blood pressure-lowering medication, mainly according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C3Research).

The researchers found that the renin-inhibitor aliskiren tended to slow coronary disease progression and reduced the risk of death, stroke and heart attack in these patients by about 50 percent, compared to placebo, suggesting that patients with prehypertension may benefit from blood pressure lowering drugs.

The results of the AQUARIUS (Aliskerin Quantitative Atherosclerosis Regression Intravascular Ultrasound Study) trial were presented at the European Society of Cardiology Congress 2013 and published simultaneously in the Journal of the American Medical Association.

Aliskiren affects the body's renin-angiotensin-aldosterone system (RAAS), a hormone system that regulates blood pressure and has been shown in prior studies to play an important role in the development of atherosclerosis, or the hardening or clogging of the arteries. As a renin inhibitor, aliskiren partially blocks renin from triggering the RAAS process and is approved to treat hypertension to optimal guidelines of 140/90 mmHg, or the high end of the prehypertensive range